Ottavi di finale
26.10.2021 12:00 FC Sfîntul Gheorghe FC Sfîntul Gheorghe - Victoria Bardar Victoria Bardar -:-
26.10.2021 12:00 CS Petrocub CS Petrocub - Olimp Comrat Olimp Comrat -:-
26.10.2021 12:00 Sparta Selemet Sparta Selemet - Dinamo Auto Dinamo Auto -:-
26.10.2021 14:00 CSF Bălţi CSF Bălţi - FC Cahul 2005 FC Cahul 2005 -:-
27.10.2021 12:00 FC Floreşti FC Floreşti - FC Sîngerei FC Sîngerei -:-
27.10.2021 12:00 Speranța Drochia Speranța Drochia - FC Zimbru FC Zimbru -:-
27.10.2021 14:00 FC Milsami FC Milsami - FCM Ungheni FCM Ungheni -:-
27.10.2021 14:00 FC Sheriff FC Sheriff - FC Saxan FC Saxan -:-