1. Giornata 10.08.2019 Burnley FC - Southampton FC 3:0
2. Giornata 17.08.2019 Southampton FC - Liverpool FC 1:2 Gol
3. Giornata 24.08.2019 Brighton & Hove Albion - Southampton FC 0:2
4. Giornata 31.08.2019 Southampton FC - Manchester United 1:1
5. Giornata 14.09.2019 Sheffield United - Southampton FC 0:1
6. Giornata 20.09.2019 Southampton FC - AFC Bournemouth 1:3
7. Giornata 28.09.2019 Tottenham Hotspur - Southampton FC 2:1 Gol
8. Giornata 06.10.2019 Southampton FC - Chelsea FC 1:4 Gol
9. Giornata 19.10.2019 Wolverhampton Wanderers - Southampton FC 1:1 Gol
10. Giornata 25.10.2019 Southampton FC - Leicester City 0:9
11. Giornata 02.11.2019 Manchester City - Southampton FC 2:1
12. Giornata 09.11.2019 Southampton FC - Everton FC 1:2 Gol
13. Giornata 23.11.2019 Arsenal FC - Southampton FC 2:2 Gol cartellino giallo
14. Giornata 30.11.2019 Southampton FC - Watford FC 2:1 Gol
15. Giornata 04.12.2019 Southampton FC - Norwich City 2:1 Gol
16. Giornata 08.12.2019 Newcastle United - Southampton FC 2:1 Gol
17. Giornata 14.12.2019 Southampton FC - West Ham United 0:1
18. Giornata 21.12.2019 Aston Villa - Southampton FC 1:3 GolGol
19. Giornata 26.12.2019 Chelsea FC - Southampton FC 0:2
20. Giornata 28.12.2019 Southampton FC - Crystal Palace 1:1 Gol
21. Giornata 01.01.2020 Southampton FC - Tottenham Hotspur 1:0 Gol
22. Giornata 11.01.2020 Leicester City - Southampton FC 1:2 Gol cartellino giallo
23. Giornata 18.01.2020 Southampton FC - Wolverhampton Wanderers 2:3
24. Giornata 21.01.2020 Crystal Palace - Southampton FC 0:2
25. Giornata 01.02.2020 Liverpool FC - Southampton FC 4:0
26. Giornata 15.02.2020 Southampton FC - Burnley FC 1:2 Gol
27. Giornata 22.02.2020 Southampton FC - Aston Villa 2:0
28. Giornata 29.02.2020 West Ham United - Southampton FC 3:1
29. Giornata 07.03.2020 Southampton FC - Newcastle United 0:1
30. Giornata 19.06.2020 Norwich City - Southampton FC 0:3 Gol cartellino giallo
31. Giornata 25.06.2020 Southampton FC - Arsenal FC 0:2
32. Giornata 28.06.2020 Watford FC - Southampton FC 1:3 GolGol